High-Performance Liquid Chromatograph

In addition to the reliability and stability afforded by the proven core capabilities of the i-Series, its remote monitoring functions which employ smart devices, and its ICM, which allows all necessary operations from setup of the samples to the start of analysis to be performed on the instrument itself, have eliminated the troublesome analysis operations that needed to be made on a computer in the laboratory, achieving a computer-less laboratory.

Description

  • ICM (Interactive Communication Mode) to free operators from the laboratory
  • Remote monitoring regardless of operating environment
  • Maximum reliability and stability
    • Dual temp-control with TC-Optics and flow cells unaffected by room temperature fluctuation
    • Excellent micro injection volume reproducibility of 1 µL or less
    • Ultrafast injection cycle reduces analysis times

  • Equipped with pretreatment functions that automatically produce dilutions, add reagents, etc.
  • Unified graphical user interface between system and workstation
  • Create analytical sequences on visualized vial positions: Quick batch function

  • Automation of a number of routine analysis procedures
  • Migrate existing methods from either Shimadzu or non-Shimadzu systems

 

The Nexera-i is a simple, all-in-one UHPLC system that raises the productivity of the laboratory to the maximum by reducing the time needed to develop analysis methods, and by simplifying the work needed to transfer already proven method files. Up to 1,536 samples can set up at once, so CMC related analyses that require many samples, or a wide variety of other analyses, such as dissolution tests, pharmacokinetics, and toxicant tests can be speedily accomplished, thus reducing the time needed. Moreover, the automatic shutdown function of the i-Series has resulted in a reduction of more than 95 % (compared with Shimadzu existing systems) in the power consumption of the instrument when in the standby state, contributing to reducing the environmental impact.


Nexera-i MT i-Series Method Transfer System

This system contains two flow lines, matched to the volumes of each of UHPLC and HPLC systems. In addition to simplifying the migration of analytical test methods for customers using HPLC, this enables the smooth transfer of customer’s HPLC methods to faster UHPLC methods. It enables analytical test methods established with nonShimadzu HPLC to be migrated with excellent repeatability, significantly reducing the process of validating analytical methods. The newly developed Condition Transfer and Optimization (ACTO) function incorporated in LabSolutions allows users to transfer injection timings matched to differences in system volumes between instruments, without editing the concentration gradient programs in existing methods. Furthermore, existing HPLC methods can simply be loaded for transfer to faster Nexera-i MT methods.

 


The Prominence ™ -i is an all-in-one LC system that can be operated intuitively regardless of the level of the operator’s experience. This feature of course builds upon its reliable and stable core features. Information such as the real-time display of the chromatogram for the ongoing analysis or the current status of the instrument can be viewed at a glance. A navigation function allows for monitoring the usage frequency of consumables and assists with replacement procedures. This reduces the time for maintenance needed for the instrument and increases the operation rate. Additionally, due to the optimum system capacity, analysis method files used on existing HPLC systems can be transferred smoothly. It is well suited as a specialized analyzer for routine tasks such as checking synthetic materials or performing quantitative tests in accordance with pharmacopoeia.

 

Prominence-i LT Detectorless Model

The Prominence-i series LC-2030C LT detectorless model is an integrated LC system without a UV detector or a PDA detector. This model enhances the selectivity of the detector used, while maintaining the advantages of the i-Series, including space-saving feature, operability from a touch panel, and both fast injection & excellent reproducibility at trace injection volumes. In addition, upgrades to faster analysis are enabled by using an extension kit that provides the same pressure capacity as the Nexera-i. It can be used as an LC-MS front-end LC for the analysis of sugars and amino acids, which do not absorb UV, for GPC analysis of polymers using a RID detector, and for fluorescence analysis of anionic surfactants in an aqueous environment.